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Thermo Fisher
microarray suite (mas v5.0 ![]() Microarray Suite (Mas V5.0, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/result/microarray suite (mas v5.0/product/Thermo Fisher Average 90 stars, based on 1 article reviews
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Image Search Results
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research
Article Title: The investigational Aurora kinase A inhibitor MLN8237 induces defects in cell viability and cell cycle progression in malignant bladder cancer cells in vitro and in vivo
doi: 10.1158/1078-0432.CCR-12-2383
Figure Lengend Snippet: Mitotic spindle checkpoint genes are broadly overexpressed in human urothelial carcinoma. A, Human samples of normal urothelium (N=10) and urothelial carcinoma of the bladder (N=8) were subjected to RNA microarray. A subset of 13 gene transcripts related to the mitotic spindle checkpoint, including Aurora A and B, were upregulated at least 5-fold in the urothelial carcinoma compared to the normal urothelium. B, Upregulation of these genes was validated by two-step quantitative real-time PCR on a separate set of human samples of urothelial carcinoma (N=3) and normal urothelium (N=3). 10 of 13 genes (asterisked) demonstrated statistical significance (T-test P-value < 0.05) for differential expression in urothelial carcinoma compared to normal urothelium.
Article Snippet: Expression values were generated by using
Techniques: Microarray, Real-time Polymerase Chain Reaction, Expressing